Bulk anti-Human MHC Class I antibody (W6/32) - Low Endotoxin

Bulk anti-Human MHC Class I antibody (W6/32) - Low Endotoxin

Catalog Number:
A001437211ICH
Mfr. No.:
ICH1023
Price:
$680
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      • Overview
        • Antigen Distribution: This HLA-A, B, C antigen is present on most nucleated cells of humans and old world monkeys.
          Specificity: Anti-MHC Class I In Vivo Antibody - Low Endotoxin (W6/32) recognizes/reacts with major histocompatibility complex (MHC) class I, HLA-A, B, and C
          Purification method: This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
          Isotype Control: Mouse IgG2a In Vivo Isotype Control - Low Endotoxin [C1.18.4] (ICH2245)
          Endotoxin: ≤ 1.0 EU/mg as determined by the LAL method
          Aggregation: Aggregation level ≤ 5%

          Please contact us at for specific academic pricing.

          Background

          MHC class I antigens associated with β2-microglobulin are expressed by all human nucleated cells. MHC class I molecules are involved in the presentation of antigens to CD8+ T cells and plays a central role in cell-mediated immune responses and tumor surveillance.

      • Properties
        • Host
          mouse
          Isotype
          IgG2a
          Reactivity
          human
          Clone
          W6/32
          Immunogen
          Human tonsil cell membrane
          Purification
          >95% by SDS-PAGE and HPLC
          Formulation
          No carrier proteins or preservatives in 0.01 M phosphate buffered saline (PBS) pH 7.2 - 7.4, 150 mM NaCl.
          Storage
          anti-MHC Class I In Vivo Antibody - Low Endotoxin (W6/32) is stable for at least six (6) weeks when stored sterile at 2-8°C. For long-term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
          Molecular Weight
          1.0 mg/ml
          Regulatory Status
          Each investigator should determine their own optimal working dilution for specific applications.

          * Products are for research use only. Not for use in diagnostic or therapeutic procedures.

      • Applications
        • Application
          WB; Flow Cytometry; Immunoprecipitation; Functional Assays; IHC (frozen)

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