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Overview
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Antigen Distribution: FcγRI (CD64) is an IgG receptor expressed by monocytes and myeloid cell lines.
Specificity: Clone 10.1 recognizes an epitope on human FcγRI
Purification method: This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Isotype Control: Mouse IgG1 Isotype Control for In Vivo - Low Endotoxin [HKSP] (ICH2247)
Endotoxin: ≤ 0.75 EU/mg as determined by the LAL method
Aggregation: Aggregation level ≤ 1%Please contact us at for specific academic pricing.
Background
Fc gamma receptors (FcγRs) are membrane-bound proteins which control and mediate communication of IgG antibodies within the immune system. These receptors play a crucial role in the link between the innate and adaptive immune system. FcγRI, CD64, is expressed on dendritic cells, macrophages/monocytes, and granulocytes. Of the FcγRs, FcγRI is capable of interacting with monomeric IgG with relatively high affinity.
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