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Overview
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Background
Essential component of the mitotic checkpoint. Required for normal mitosis progression. The mitotic checkpoint delays anaphase until all chromosomes are properly attached to the mitotic spindle. One of its checkpoint functions is to inhibit the activity of the anaphase-promoting complex/cyclosome (APC/C) by blocking the binding of CDC20 to APC/C, independently of its kinase activity. The other is to monitor kinetochore activities that depend on the kinetochore motor CENPE. Required for kinetochore localization of CENPE.
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- Properties
- Applications
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Overview
BubR1 Rabbit mAb
BubR1 Rabbit mAb
Catalog Number:
A001550785RED
Mfr. No.:
RDSA67382
Price:
$470
Size:
100μL
Quantity:
Add to Cart:
.