Biotin-Ub-PA

Biotin-Ub-PA

Catalog Number:
UULP097774UBP
Mfr. No.:
M1020
Price:
$448
  • Size:
    25 µg
    Quantity:
    Add to Cart:
      • Overview
        • Biotin-Ub-PA is a newly developed potent and specific inhibitor of deubiquitinating enzymes (DUBs), which has a N-terminal biotin tag. An aminohexanoic acid (Ahx) linker is used to create extra space between the biotin and Ub protein for efficient access of the biotin binding entity. This activity probe can be used for activity profiling experiments and determining DUB inhibitor specificity. It has two unique capabilities: it forms a covalent linkage with the active site Cys residue of a DUB that can be cleaved by acid treatment (5% aq. TFA), allowing for proteomic analyses. Biotin-Ub-PA targets all three major DUB families: UCH, USP and OTU

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      • Properties
        • Source
          Synthetic
          Formulation
          Product in lyophilized powder form.
          Storage
          Powder at −20°C; solution at −80°C. Avoid multiple freeze/thaw cycles.
          Concentration
          N/A
          Molecular Weight
          8885 Da by MS

          * Research Use Only

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