Biotin Annexin V

Biotin Annexin V

Catalog Number:
CFA1108810IMM
Mfr. No.:
ANXVB-200T
Price:
$662
  • Size:
    200 test
    Quantity:
    Add to Cart:
      • Overview
        • Apoptosis is characterized by a variety of morphological features. One of the earliest indications of apoptosis is the translocation of the membrane phospholipid phosphatidylserine (PS) from the inner to the outer leaflet of the plasma membrane. Once exposed to the extracellular environment, binding sites on PS become available for Annexin V, a 35-36 kDa, Ca 2+-dependent, phospholipid binding protein with a high affinity for PS. The translocation of PS precedes other apoptotic processes such as loss of plasma membrane integrity, DNA fragmentation, and chromatin condensation. As such, Annexin V can be conjugated to biotin or to a fluorochrome, and used for the easy, flow cytometric identification of cells in the early stages of apoptosis. Aplication Reference|

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      • Properties
        • Categories
          Apoptosis Detection
          Alternative Name
          Annexin A5
          Molecular Weight
          35.9 kDa
          Other Properties
          Conjugated: Biotin
          Gene ID: 308
          Storage
          The reagent is provided in aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium azide (NaN3). Store in the dark at 2-8 °C.
          Regulatory Status
          RUO

          * For research use only.

      • Applications
        • Application
          Flow Cytometry

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