Name: Benfotiamine
Price: 161.00 USD

- Overview
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    Background
    
    Benfotiamine, the lipid-soluble thiamine derivative used as a treatment for diabetic neuropathy, can inhibit three major pathways(the hexosamine pathway, the advanced glycation end product (AGE) formation pathway and the diacylglycerol (DAG)?protein kinase C (PKC) pathway）of hyperglycemic damage and prevent experimental diabetic retinopathy. Benfotiamine is a synthetic S-acyl derivative of thiamine (vitamin B1) for treating sciatica and other painful nerve conditions. More effective at increasing thiamin levels in blood and tissues than water-soluble salts like the previous vitamin B1.
- Properties
  - Categories
    
    Drug for painful nerve condition
    
    Alternative Name
    
    S-Benzoylthiamine O-monophosphate; S-[(Z)-2-[(4-amino-2-methylpyrimidin-5-yl)methyl-formylamino]-5-phosphonooxypent-2-en-3-yl] benzenecarbothioate
    
    CAS Number
    
    22457-89-2
    
    Molecular Formula
    
    C19H23N4O6PS
    
    Molecular Weight
    
    466.45
    
    Appearance
    
    A solid
    
    Purity
    
    99.76%
    
    Solubility
    
    insoluble in H2O; insoluble in EtOH; insoluble in DMSO
    
    Storage
    
    Store at -20°C
    
    SMILES
    
    CC1=NC=C(C(=N1)N)CN(C=O)C(=C(CCOP(=O)(O)O)SC(=O)C2=CC=CC=C2)C
    
    * For Research Use Only