Bcl-6 Rabbit mAb

Bcl-6 Rabbit mAb

Catalog Number:
A001549966RED
Mfr. No.:
RDSA66564
Price:
$470
  • Size:
    100μL
    Quantity:
    Add to Cart:
    Add to Cart
      • Overview

        • Please contact us at for specific academic pricing.

          Background

          Bcl-6, a transcriptional repressor, binds Stat recognition-like DNA elements and influences germinal center development and cell differentiation. Additionally, Bcl-6 negatively regulates NFκB expression, thereby inhibiting NFκB-mediated cellular functions. HDAC- and silent information regulator (SIR)-2-dependent acet-ylation of Bcl-6 causes downregulation of activity by inhibiting the ability of Bcl-6 to recruit complexes containing histone deacetylases (HDACs).

      • Properties
        • Host
          rabbit
          Antibody Type
          monoclonal
          Isotype
          IgG
          Reactivity
          human
          Immunogen
          A synthesized peptide derived from human Bcl6
          Purification
          Affinity purification
          Conjugate
          Unconjugated
          Formulation
          Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
          Storage
          Store at -20°C. Avoid freeze / thaw cycles.
          Antigen
          B-cell lymphoma 6 protein;BCL-6;B-cell lymphoma 5 protein;BCL-5;Protein LAZ-3;Zinc finger and BTB domain-containing protein 27;Zinc finger protein 51;BCL6;BCL5;LAZ3;ZBTB27;ZNF51 (UniProt:P41182)

          * This product is for Research Use Only.

      • Applications
        • Application
          WB; IHC; ICC/IF; IP
        • Application Dilutions
          WB 1:500-1:2000
          IHC 1:50-1:200
          ICC/IF 1:50-1:200
          IP 1:50

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