BCL-2(Phospho-Ser70) Antibody

BCL-2(Phospho-Ser70) Antibody

Catalog Number:
A001548094RED
Mfr. No.:
RDSA62068
Price:
$483
  • Size:
    100μL
    Quantity:
    Add to Cart:
      • Overview
        • Please contact us at for specific academic pricing.

          Background

          Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).

      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human
          Immunogen
          Peptide sequence around phosphorylation site of serine 70(R-T-S(p)-P-L) derived from Human BCL-2.
          Purification
          Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatography using non-phosphopeptide.
          Conjugate
          Unconjugated
          Formulation
          Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
          Storage
          Store at -20°C. Avoid freeze / thaw cycles.
          Concentration
          1.0 mg/mL
          Molecular Weight
          26kDa (Observed)
          Antigen
          Bcl-2;PPP1R50 (Gene ID:596; UniProt:P10415)

          * This product is for Research Use Only.

      • Applications
        • Application
          IHC
        • Application Dilutions
          IHC 1:50-1:100

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