Bazedoxifene acetate

Bazedoxifene acetate

Catalog Number:
FC01364826APE
Mfr. No.:
APE-A3233
Price:
$220
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      • Overview
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          Background

          Bazedoxifene, a novel selective estrogen receptor modulator (SERM), has been developed to have favorable effects on bone and the lipid profile while minimizing stimulation of uterine or breast tissues. Two large Phase III clinical trials showed that Bazedoxifene, as well as raloxifene, increased bone mineral density, decreased levels of bone turnover markers, and significantly reduced the risk of new vertebral fractures in postmenopausal women compared with placebo.

      • Properties
        • Categories
          Estrogen receptor modulator
          Alternative Name
          Viviant, WAY-140424, WAY-TES 424, Conbriza, TSE-424,; acetic acid;1-[[4-[2-(azepan-1-yl)ethoxy]phenyl]methyl]-2-(4-hydroxyphenyl)-3-methylindol-5-ol
          CAS Number
          198481-33-3
          Molecular Formula
          C32H38N2O5
          Molecular Weight
          530.65
          Appearance
          A solid
          Purity
          98.00%
          Solubility
          insoluble in H2O; ≥182 mg/mL in DMSO; ≥8.483 mg/mL in EtOH with gentle warming and ultrasonic
          Storage
          Store at -20°C
          SMILES
          CC1=C(N(C2=C1C=C(C=C2)O)CC3=CC=C(C=C3)OCCN4CCCCCC4)C5=CC=C(C=C5)O.CC(=O)O

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