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Overview
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Background
Bax is a key component for cellular induced apoptosis through mitochondrial stress. Upon apoptotic stimulation, Bax forms oligomers and translocates from the cytosol to the mitochondrial membrane. Through interactions with pore proteins on the mitochondrial membrane, Bax increases the membrane's permeability, which leads to the release of cytochrome c from mitochondria, activation of caspase-9 and initiation of the caspase activation pathway for apoptosis.
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- Properties
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Overview
Bax Rabbit mAb
Bax Rabbit mAb
Catalog Number:
A001549891RED
Mfr. No.:
RDSA66489
Price:
$470
Size:
100μL
Quantity:
Add to Cart:
.