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Overview
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Endogenous MRGPRX1 agonist.
BAM 22P is a potent endogenous agonist, derived from the proenkephalin A gene, for the Mas-related G protein-coupled receptor X1 (MRGPRX1), which was originally isolated from bovine adrenal medulla. BAM 22P is a potent opioid agonist with an IC50 of 1.3 nM in guinea pig ileum. BAM 22P can produces opioid- and non-opioid receptor mediated antinociceptive effects in vivo.
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Overview