BAFF His Recombinant Protein

BAFF His Recombinant Protein

Catalog Number:
P001411918ABE
Mfr. No.:
Abe32-1075
Price:
  • Size:
    20 µg
    Quantity:
    Add to Cart:
      • Overview
        • BLyS Human Recombinant fused to His tag at N-terminus produced in E. Coli is a single, non-glycosylated polypeptide chain containing 190 amino acids and having a molecular mass of 21 kDa. The BAFF His tag fusion protein is purified by proprietary chromatographic techniques. Binds to tnfrsf13b/taci and tnfrsf17/bcma. tnfsf13/april binds to the same 2 receptors, together, they form a 2 ligands -2 receptors pathway involved in the stimulation of b- and t-cell function and the regulation of humoral immunity. a third b-cell specific baff-receptor (baffr/br3) promotes the survival of mature b-cells and the b-cell response. B Lymphocyte Stimulator functions as a potent B-cell growth factor in costimulation assays. Administration of BAFF Human recombinant to mice disrupts splenic B-cell and T-cell zones and results in elevated levels of serum immunoglobulin.

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      • Properties
        • Protein Name
          BAFF, BLYS, CD257, TALL1, THANK, ZTNF4, TALL-1, TNFSF20, TNFSF13B, B-cell Activating Factor.
          Source
          E. coli
          Type
          Recombinant Proteins
          Purification
          Greater than 95.0% as determined by (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
          Formulation
          Recombinant His Tag BAFF contains 20mM Tris buffer pH-8 and 5mM DTT.
          Storage
          BLyS although stable at 10°C for 3 weeks, should be stored desiccated below -18°C. Please prevent freeze-thaw cycles.

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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