rActivin A Recombinant Protein

rActivin A Recombinant Protein

Catalog Number:
P001411920ABE
Mfr. No.:
Abe32-1009
Price:
  • Size:
    10 µg
    Quantity:
    Add to Cart:
      • Overview
        • Activins are homodimers or heterodimers of the different Beta subunit isoforms, part of the TGF Beta family. Mature Activin A has two 116 amino acids residues BetaA subunits ( BetaA- BetaA). Activin displays an extensive variety of biological activities, including mesoderm induction, neural cell differentiation, bone remodelling, haematopoiesis, and reproductive physiology. Activins takes part in the production and regulation of hormones such as FSH, LH, GnRH and ACTH. Cells that are identified to express Activin A include fibroblasts, endothelial cells, hepatocytes, vascular smooth muscle cells, macrophages, keratinocytes, osteoclasts, bone marrow monocytes, prostatic epithelium, neurons, chondrocytes, osteoblasts, Leydig cells, Sertoli cells, and ovarian granulosa cells.

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      • Properties
        • Protein Name
          Inhba, Inhibin beta A, FSH releasing protein.
          Source
          E. coli
          Type
          Recombinant Proteins
          Purification
          Greater than 95% as obsereved by SDS-PAGE.
          Formulation
          Rat Activin-A was lyophilized from a concentrated 1mg/ml protein solution containing 0.02% TFA.
          Storage
          Lyophilized Activin-A although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Activin-A should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
          Activity
          Biological Activity is assessed by the ability to induce cytoxicity of MPC-11 cells and was found to be 1-1.5 ng/ml corresponding to a specific activity of 666,667-1,000,000 Units/mg.

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

      • Applications
        • Application Description
          Rat INHBA protein should be reconstituted in distilled pyrogen free water to a concentration of 100ug /ml which can then be further diluted to other aqueous solutions. Biological activity is assessed by the ability to induce cytoxicity of MPC-11 cells and was found to be 1-1.5 ng/ml corresponding to a specific activity of 666,667-1,000,000 Units/mg.

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