Login / Register
0

Azido-PEG4-acid

Azido-PEG4-acid

Catalog Number:
PTC1441462INV
Mfr. No.:
V12194
Price:
Inquiry
  • Size:
    Quantity:
    Add to Cart:
    Add to Cart
      • Overview

        • Azido-PEG4-acid is a PEG analogue containing an azide group and is used as a PROTAC linker for the synthesis of Rucaparib-based PARP PROTAC degraders. With a terminal carboxylic acid, it is also a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). The hydrophilic PEG spacer increases solubility in aqueous media. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond.

          Please contact us at for specific academic pricing.

      • Properties
        • Categories
          PROTAC Linkers
          CAS Number
          1257063-35-6
          Molecular Formula
          C11H21N3O6
          Molecular Weight
          291.3
          Purity
          ≥98%
          Storage
          Powder: store in -20°C freezer for up to three years, store in 4°C freezer for up to two years
          In solvent: store in -80°C freezer for up to six months, store in -20°C freezer for up to two months
          Shipping
          Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
          SMILES
          C(COCCOCCOCCOCCN=[N+]=[N-])C(=O)O

          * For research use only

    We Also Recommend

    Azido-PEG4-alcohol

    Azido-PEG4-alcohol

    Azido-PEG4-amine

    Azido-PEG4-amine

    Azido-PEG5-alcohol

    Azido-PEG5-alcohol

    Note: If you don't receive our verification email, do the following:

    • Confirm that you entered your email address correctly.
    • Check if the email is in your spam or junk folder.
    • Or you may contact us at .
    • Products
    Amerigo Scientific
    Support
    Contact Us
    Copyright © Amerigo Scientific. All rights reserved.