Azido-dPEG®₁₁-amine

Azido-dPEG®11-amine, product number 10524, is a water-soluble, biocompatible product. It can function either as a heterobifunctional click chemistry crosslinker or as a homobifunctional carbonyl-reactive crosslinker. An azide group and an amine group terminate opposite ends of a single molecular weight, discrete polyethylene glycol (dPEG®) chain. Alkynes react with the azido group in copper-catalyzed, ruthenium-catalyzed, and strain-promoted azide-alkyne cycloaddition reactions to yield triazoles. Also, the azide group can act as a masked amine that reduces to a primary amine via a suitable reducing agent. Furthermore, Azido-dPEG®11-amine can participate in a Staudinger ligation with appropriate phosphine derivatives to create a water-soluble conjugate.


dPEG® Technology Makes a Difference in PEGylation
Quanta BioDesign invented discrete PEG technology. We manufacture and sell our products under the dPEG® trade name. Our products provide all of the benefits of conventional PEG linkers and spacers. However, unlike traditional polymer PEGylation reagents, our products have no dispersity. Thus, our products eliminate the analytical difficulties that traditional PEGylation reagents produce.

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