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Overview
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Background
ATF4, an activating transcription factor/cAMP-response element-binding protein family member, functions in the PERK and eIF2α ER stress responsive pathway. ER stress represses the translation of the majority of mRNAs, but selectively stimulates the translation of certain mRNAs including that of ATF-4. Induced expression of ATF-4 increases the expression of genes critical for the recovery from ER stress.
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Overview
ATF4 Rabbit mAb
ATF4 Rabbit mAb
Catalog Number:
A001550448RED
Mfr. No.:
RDSA67045
Price:
$470
Size:
100μL
Quantity:
Add to Cart: