Arctiin

Arctiin

Catalog Number:
NP01367465APE
Mfr. No.:
APE-N1627
Price:
$180
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      • Overview
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          Background

          (-)-Arctiin is a lignan derivative with antitumor activities acting as a potent inhibitor of HIV-I integrase and DNA topoisomerase II. (-)-Arctiin down-regulates anti-apoptotic protein Bcl-XL. (-)-Arctiin has been shown to exhibit phytoestrogenic activity

      • Properties
        • Categories
          HIV-I integrase/DNA topoisomerase II inhibitor
          Alternative Name
          (3R,4R)-4-[(3,4-dimethoxyphenyl)methyl]-3-[[3-methoxy-4-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]methyl]oxolan-2-one
          CAS Number
          20362-31-6
          Molecular Formula
          C27H34O11
          Molecular Weight
          534.55
          Appearance
          A solid
          Purity
          98.00%
          Solubility
          ≥23.3 mg/mL in DMSO; insoluble in H2O; ≥17.23 mg/mL in EtOH with ultrasonic
          Storage
          Store at -20°C
          SMILES
          O[[email protected]@H]1[[email protected]@H](O)[[email protected]@H]([[email protected]@H](CO)O[[email protected]]1OC(C=C2)=C(OC)C=C2C[[email protected]@H](C(OC3)=O)[[email protected]]3CC4=CC(OC)=C(OC)C=C4)O

          * For Research Use Only

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