Arctigenin

Arctigenin

Catalog Number:

FC01367268APE

Mfr. No.:

APE-N2399

Price:

$180

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- Overview
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    Background
    
    Antioxidant, anti-inflammatory, antiproliferative and antiviral agent. Inhibits LPS-induced iNOS expression via inhibition of IκBα phosphorylation and p65 nuclear translocation (IC50 = 10 nM). Inhibits HIV-1 replication in vitro. Also potently inhibits MKK1 (MEK1) (IC50 = 0.5 nM) and provides neuroprotection by binding to kainate receptors.
- Properties
  - Categories
    
    Anti-inflammatory, antiproliferative
    
    Alternative Name
    
    (-)-Arctigenin; (3R,4R)-4-[(3,4-dimethoxyphenyl)methyl]-3-[(4-hydroxy-3-methoxyphenyl)methyl]oxolan-2-one
    
    CAS Number
    
    7770-78-7
    
    Molecular Formula
    
    C21H24O6
    
    Molecular Weight
    
    372.41
    
    Appearance
    
    A solid
    
    Purity
    
    98.00%
    
    Solubility
    
    insoluble in H2O; insoluble in EtOH; ≥17.2 mg/mL in DMSO
    
    Storage
    
    Desiccate at -20°C
    
    SMILES
    
    O=C1OC[C@](CC2=CC=C(OC)C(OC)=C2)[C@]1CC(C=C3OC)=CC=C3O
    
    * For Research Use Only

Documents

COA (Certificate Of Analysis)

MSDS (Material Safety Data Sheet)

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