Arctigenin

Arctigenin

Catalog Number:
FC01367268APE
Mfr. No.:
APE-N2399
Price:
$180
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      • Overview
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          Background

          Antioxidant, anti-inflammatory, antiproliferative and antiviral agent. Inhibits LPS-induced iNOS expression via inhibition of IκBα phosphorylation and p65 nuclear translocation (IC50 = 10 nM). Inhibits HIV-1 replication in vitro. Also potently inhibits MKK1 (MEK1) (IC50 = 0.5 nM) and provides neuroprotection by binding to kainate receptors.

      • Properties
        • Categories
          Anti-inflammatory, antiproliferative
          Alternative Name
          (-)-Arctigenin; (3R,4R)-4-[(3,4-dimethoxyphenyl)methyl]-3-[(4-hydroxy-3-methoxyphenyl)methyl]oxolan-2-one
          CAS Number
          7770-78-7
          Molecular Formula
          C21H24O6
          Molecular Weight
          372.41
          Appearance
          A solid
          Purity
          98.00%
          Solubility
          insoluble in H2O; insoluble in EtOH; ≥17.2 mg/mL in DMSO
          Storage
          Desiccate at -20°C
          SMILES
          O=C1OC[[email protected]](CC2=CC=C(OC)C(OC)=C2)[[email protected]]1CC(C=C3OC)=CC=C3O

          * For Research Use Only

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