Antimycin A3

- Overview
  - Antimycin A3 is a homologue of the antimycin complex, first isolated in 1958 from Streptomyces blastimyceticus and co-produced with antimycin A4. Antimycin A3 is a more polar analogue of A1 and A2. Antimycin A3 exhibits broad biological activity as an antifungal, anthelmintic, insecticidal, antiviral and antitumor active. Lack of availability of the individual antimycin components has hindered greater understanding of the common and unique molecular targets of the components of the antimycin complex.
    
    Antimycin A3 is soluble in ethanol, methanol, DMF and DMSO.
    
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    Background
    
    Antimycin A3 is a potent inhibitor of respiration by inhibiting the oxidation of ubiquinol to ubiquinone.
- Properties
  - CAS Number
    
    522-70-3
    
    Molecular Formula
    
    C26H36N2O9
    
    Molecular Weight
    
    520.6
    
    Appearance
    
    White solid
    
    Storage
    
    -20°C
    
    * For research use only