Name: Anti-XRCC4 antibody
Price: 224.00 USD

Overview
- XRCC4 is a protein encoded by the XRCC4 gene which is approximately 38, 2 kDa. XRCC4 is localised to the nucleus. It is involved in the HIV life cycle, DNA double-strand break repair, SUMOylation and metabolism of proteins. It functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand breaks. It plays a role in both non-homologous end joining and the completion of V(D)J recombination. XRCC4 is expressed in the bone marrow, liver and blood. Mutations in the XRCC4 gene may result in endocrine dysfunction. STJ96988 was developed from clone 5C10 and was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. The antibody detects endogenous XRCC4 proteins.
  
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Properties
- Host
  
  mouse
  
  Antibody Type
  
  monoclonal
  
  Isotype
  
  IgG1
  
  Reactivity
  
  human
  
  Clone
  
  5C10
  
  Immunogen
  
  Synthetic Peptide
  
  Purification
  
  The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS, pH 7.4, containing 0.5% BSA, 0.02% sodium azide and 50% Glycerol.
  
  Storage
  
  Store at -20°C and avoid repeat freeze-thaw cycles.
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  Dna Repair Protein Xrcc4; X-Ray Repair Cross-Complementing Protein 4 (Gene ID:7518; UniProt:Q13426)
  
  * For research use only