Anti-XRCC1 antibody

Anti-XRCC1 antibody

Catalog Number:
A001035332STJ
Mfr. No.:
STJ26128
Price:
$297
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      • Overview
        • The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.

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      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human; mouse
          Immunogen
          Recombinant fusion protein containing a sequence corresponding to amino acids 1-320 of human XRCC1 (NP_006288. 2).
          Purification
          Affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
          Storage
          Store at -20°C and avoid freeze-thaw cycles.
          Regulatory Status
          RUO
          Antigen
          Dna Repair Protein Xrcc1; X-Ray Repair Cross-Complementing Protein 1 (Gene ID:7515; UniProt:P18887)

          * For research use only

      • Applications
        • Application
          WB; IF
        • Application Dilutions
          WB 1:1000-1:2000
          IF 1:50-1:200

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