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Overview
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V-ATPase D1 is a protein encoded by the ATP6V0D1 gene which is approximately 40, 3 kDa. V-ATPase D1 is localised to the cell membrane and is involved in insulin receptor recycling, unfolded protein response, innate immune system, lysosome and metabolism. It is a multi-subunit enzyme that mediates acidification of eukaryotic intracellular organelles. This is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase D1 is ubiquitously expressed. STJ96391 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of V-ATPase D1 protein.
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Overview