Anti-EEA1 antibody

Catalog Number:

A001051763STJ

Mfr. No.:

STJ96393

Price:

$224

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Overview
- EEA1 is a protein encoded by the EEA1 gene which is approximately 162, 5 kDa. EEA1 is localised to the cytoplasm and is involved in the innate immune system, activated TLR4 signalling and sorting endosome formation in CF. It binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in endosomal trafficking. EEA1 is expressed in the liver, eye, heart, pancreas and adrenal gland. Mutations in the EEA1 gene may result in Bartonellosis and Cutaneous Lupus Erythematosus. STJ96393 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of EEA1 protein.
  
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Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human; mouse
  
  Immunogen
  
  Synthesized peptide derived from human EEA1.
  
  Purification
  
  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  
  Storage
  
  Store at -20°C and avoid repeat freeze-thaw cycles.
  
  Concentration
  
  1 mg/ml
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  Early Endosome Antigen 1; Endosome-Associated Protein P162; Zinc Finger Fyve Domain-Containing Protein 2 (Gene ID:8411; UniProt:Q15075)
  
  * For research use only