Name: Anti-UHRF2 antibody
Price: 297.00 USD

Overview
- This gene encodes a nuclear protein which is involved in cell-cycle regulation. The encoded protein is a ubiquitin-ligase capable of ubiquinating PCNP (PEST-containing nuclear protein), and together they may play a role in tumorigenesis. The encoded protein contains an NIRF_N domain, a PHD finger, a set-and ring-associated (SRA) domain, and a RING finger domain and several of these domains have been shown to be essential for the regulation of cell proliferation. This protein may also have a role in intranuclear degradation of polyglutamine aggregates. Alternative splicing results in multiple transcript variants some of which are non-protein coding.
  
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Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human; mouse; rat
  
  Immunogen
  
  Recombinant fusion protein containing a sequence corresponding to amino acids 441-622 of human UHRF2 (NP_690856. 1).
  
  Purification
  
  Affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  
  Storage
  
  Store at -20°C and avoid freeze-thaw cycles.
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  E3 Ubiquitin-Protein Ligase Uhrf2; Np95/Icbp90-Like Ring Finger Protein; Np95-Like Ring Finger Protein; Nuclear Protein 97; Nuclear Zinc Finger Protein Np97; Ring Finger Protein 107; Ring-Type E3 Ubiquitin Transferase Uhrf2; Ubiquitin-Like Phd And Ring Finger Domain-Containing Protein 2; Ubiquitin-Like-Containing Phd And Ring Finger Domains Protein 2 (Gene ID:115426; UniProt:Q96PU4)
  
  * For research use only