Name: Anti-TICAM1 antibody
Price: 297.00 USD

Overview
- This gene encodes an adaptor protein containing a Toll/interleukin-1 receptor (TIR) homology domain, which is an intracellular signaling domain that mediates protein-protein interactions between the Toll-like receptors (TLRs) and signal-transduction components. This protein is involved in native immunity against invading pathogens. It specifically interacts with toll-like receptor 3, but not with other TLRs, and this association mediates dsRNA induction of interferon-beta through activation of nuclear factor kappa-B, during an antiviral immune response.
  
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Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human; mouse; rat
  
  Immunogen
  
  Recombinant fusion protein containing a sequence corresponding to amino acids 20-200 of human TICAM1 (NP_891549. 1).
  
  Purification
  
  Affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  
  Storage
  
  Store at -20°C and avoid freeze-thaw cycles.
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  Tir Domain-Containing Adapter Molecule 1; Ticam-1; Proline-Rich-Vinculin And Tir Domain-Containing Protein B; Putative Nf-Kappa-B-Activating Protein 502h; Toll-Interleukin-1 Receptor Domain-Containing Adapter Protein Inducing Interferon Beta; Myd88-3; Tir Domain-Containing Adapter Protein Inducing Ifn-Beta (Gene ID:148022; UniProt:Q8IUC6)
  
  * For research use only