Anti-UBE2C antibody

Anti-UBE2C antibody

Catalog Number:
A001035909STJ
Mfr. No.:
STJ27450
Price:
$297
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      • Overview
        • The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, ubiquitin-conjugating enzymes, and ubiquitin-protein ligases. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein is required for the destruction of mitotic cyclins and for cell cycle progression, and may be involved in cancer progression. Multiple transcript variants encoding different isoforms have been found for this gene. Pseudogenes of this gene have been defined on chromosomes 4, 14, 15, 18, and 19.

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      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human
          Immunogen
          Recombinant fusion protein containing a sequence corresponding to amino acids 1-179 of human UBE2C (NP_008950. 1).
          Purification
          Affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
          Storage
          Store at -20°C and avoid freeze-thaw cycles.
          Regulatory Status
          RUO
          Antigen
          Ubiquitin-Conjugating Enzyme E2 C; (E3-Independent E2 Ubiquitin-Conjugating Enzyme C; E2 Ubiquitin-Conjugating Enzyme C; Ubch10; Ubiquitin Carrier Protein C; Ubiquitin-Protein Ligase C (Gene ID:11065; UniProt:O00762)

          * For research use only

      • Applications
        • Application
          WB; IHC; IF; IP
        • Application Dilutions
          WB 1:500-1:2000
          IHC 1:50-1:200
          IF 1:50-1:100
          IP 1:20-1:50

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