Name: Anti-TRIM25 antibody
Price: 297.00 USD

Overview
- The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to the cytoplasm. The presence of potential DNA-binding and dimerization-transactivation domains suggests that this protein may act as a transcription factor, similar to several other members of the TRIM family. Expression of the gene is upregulated in response to estrogen, and it is thought to mediate estrogen actions in breast cancer as a primary response gene.
  
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Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human; mouse
  
  Immunogen
  
  Recombinant fusion protein containing a sequence corresponding to amino acids 100-400 of human TRIM25 (NP_005073. 2).
  
  Purification
  
  Affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  
  Storage
  
  Store at -20°C and avoid freeze-thaw cycles.
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  E3 Ubiquitin/Isg15 Ligase Trim25; Estrogen-Responsive Finger Protein; Ring Finger Protein 147; Ring-Type E3 Ubiquitin Transferase; Ring-Type E3 Ubiquitin Transferase Trim25; Tripartite Motif-Containing Protein 25; Ubiquitin/Isg15-Conjugating Enzyme Trim25; Zinc Finger Protein 147 (Gene ID:7706; UniProt:Q14258)
  
  * For research use only