Anti-TNFRSF10A antibody

Catalog Number:

A001036306STJ

Mfr. No.:

STJ28189

Price:

$297

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Overview
- The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), and thus transduces cell death signal and induces cell apoptosis. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein.
  
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Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human
  
  Immunogen
  
  Recombinant fusion protein containing a sequence corresponding to amino acids 269-468 of human TNFRSF10A (NP_003835. 3).
  
  Purification
  
  Affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  
  Storage
  
  Store at -20°C and avoid freeze-thaw cycles.
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  Tumor Necrosis Factor Receptor Superfamily Member 10a; Death Receptor 4; Tnf-Related Apoptosis-Inducing Ligand Receptor 1; Trail Receptor 1; Trail-R1; Cd Antigen Cd261 (Gene ID:8797; UniProt:O00220)
  
  * For research use only