Name: Anti-TNF antibody
Price: 297.00 USD

Overview
- This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine.
  
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Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human; mouse
  
  Immunogen
  
  Recombinant fusion protein containing a sequence corresponding to amino acids 1-233 of human TNF (NP_000585. 2).
  
  Purification
  
  Affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  
  Storage
  
  Store at -20°C and avoid freeze-thaw cycles.
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  Tumor Necrosis Factor; Cachectin; Tnf-Alpha; Tumor Necrosis Factor Ligand Superfamily Member 2; Tnf-A Cleaved Into-Tumor Necrosis Factor-Membrane Form; N-Terminal Fragment; Ntf-Intracellular Domain 1; Icd1-Intracellular Domain 2; Icd2-C-Domain 1-C-Domain 2-Tumor Necrosis Factor-Soluble Form (Gene ID:7124; UniProt:P01375)
  
  * For research use only