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Overview
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The product of this gene belongs to the SNF2/RAD54 helicase family. It represents the main component of the nucleosome remodeling and deacetylase complex and plays an important role in epigenetic transcriptional repression. Patients with dermatomyositis develop antibodies against this protein. Somatic mutations in this gene are associated with serous endometrial tumors. Alternative splicing results in multiple transcript variants encoding different isoforms.
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- Properties
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Overview
Immunofluorescence analysis of L929 cells using CHD4 antibody (STJ113182) at dilution of 1:100. Blue: DAPI for nuclear staining.
Immunofluorescence analysis of U20S cells using CHD4 antibody (STJ113182) at dilution of 1:100. Blue: DAPI for nuclear staining.
Immunofluorescence analysis of C6 cells using CHD4 antibody (STJ113182) at dilution of 1:100. Blue: DAPI for nuclear staining.
Immunohistochemistry of paraffin-embedded Mouse liver using CHD4 antibody (STJ113182) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded Human oophoroma using CHD4 antibody (STJ113182) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded Rat liver using CHD4 antibody (STJ113182) at dilution of 1:100 (40x lens).
Western blot analysis of extracts of various cell lines, using CHD4 antibody (STJ113182) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 30s.
Anti-CHD4 antibody
Anti-CHD4 antibody
Catalog Number:
A001020525STJ
Mfr. No.:
STJ113182
Price:
$297
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