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Overview
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The protein encoded by this gene is a serine/threonine kinase that may be involved in the regulation of chromatin assembly. The encoded protein is only active when it is phosphorylated, and this phosphorylation is cell cycle-dependent, with the maximal activity of this protein coming during S phase. The catalytic activity of this protein is diminished by DNA damage and by blockage of DNA replication. Three transcript variants encoding different isoforms have been found for this gene.
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Overview
Immunohistochemistry of paraffin-embedded mouse brain using TLK1 antibody (STJ117031) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded rat heart using TLK1 antibody (STJ117031) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human placenta using TLK1 antibody (STJ117031) at dilution of 1:100 (40x lens).
Western blot analysis of extracts of various cell lines, using TLK1 antibody (STJ117031) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 1s.
Anti-TLK1 antibody
Anti-TLK1 antibody
Catalog Number:
A001023880STJ
Mfr. No.:
STJ117031
Price:
$297
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