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Overview
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This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last two amino acids of the carboxy-terminus have been cleaved off. Numerous pseudogenes have been reported for this gene. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
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- Properties
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Overview
Immunofluorescence analysis of U2OS cells using SUMO2 antibody (STJ25749). Blue: DAPI for nuclear staining.
Western blot analysis of extracts of various cell lines, using SUMO2 antibody (STJ25749) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.
Anti-SUMO2 antibody
Anti-SUMO2 antibody
Catalog Number:
A001035117STJ
Mfr. No.:
STJ25749
Price:
$297
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