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Overview
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Cytokine-mediated signal transduction in the JAK-STAT cascade requires the involvement of adaptor molecules. One such signal-transducing adaptor molecule contains an SH3 domain that is required for induction of MYC and cell growth. The protein encoded by this gene binds to the SH3 domain of the signal-transducing adaptor molecule, and plays a critical role in cytokine-mediated signaling for MYC induction and cell cycle progression. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene.
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- Properties
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Overview
Immunofluorescence analysis of U2OS cells using STAMBP antibody (STJ29145). Blue: DAPI for nuclear staining.
Immunohistochemistry of paraffin-embedded rat spleen using STAMBP antibody (STJ29145) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human stomach using STAMBP antibody (STJ29145) at dilution of 1:100 (40x lens).
Western blot analysis of extracts of various cell lines, using STAMBP antibody (STJ29145) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 30s.
Anti-STAMBP antibody
Anti-STAMBP antibody
Catalog Number:
A001037171STJ
Mfr. No.:
STJ29145
Price:
$297
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