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Overview
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This gene belongs to a family of Sp1 related genes that encode transcription factors that regulate transcription by binding to consensus GC-and GT-box regulatory elements in target genes. This protein contains a zinc finger DNA-binding domain and several transactivation domains, and has been reported to function as a bifunctional transcription factor that either stimulates or represses the transcription of numerous genes. Transcript variants encoding different isoforms have been described for this gene, and one has been reported to initiate translation from a non-AUG (AUA) start codon. Additional isoforms, resulting from the use of alternate downstream translation initiation sites, have also been noted. A related pseudogene has been identified on chromosome 13.
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- Properties
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Overview
Immunohistochemistry of paraffin-embedded human colon using SP3 Rabbit pAb (STJ114938) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded rat ovary using SP3 Rabbit pAb (STJ114938) at dilution of 1:100 (40x lens).
Western blot analysis of extracts of various cell lines, using SP3 antibody (STJ114938) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 30s.
Anti-SP3 antibody
Anti-SP3 antibody
Catalog Number:
A001021861STJ
Mfr. No.:
STJ114938
Price:
$297
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