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Overview
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This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT).
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- Properties
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Overview
Immunoprecipitation analysis of 200ug extracts of C6 cells using 3ug SOX2 antibody (STJ25661). Western blot was performed from the immunoprecipitate using SOX2 antibody (STJ25661) at a dilition of 1:500.
Immunofluorescence analysis of A549 cells using SOX2 antibody (STJ25661).
![Immunohistochemistry of paraffin-embedded human esophageal using [KO Validated] SOX2 Rabbit pAb (STJ25661) at dilution of 1:100 (40x lens).](https://resource.amerigoscientific.com/p-img/STJ25661_4_IHC__29398.1602784740.jpg)
Immunohistochemistry of paraffin-embedded human esophageal using [KO Validated] SOX2 Rabbit pAb (STJ25661) at dilution of 1:100 (40x lens).
![Immunohistochemistry of paraffin-embedded mouse embryos using [KO Validated] SOX2 Rabbit pAb (STJ25661) at dilution of 1:100 (40x lens).](https://resource.amerigoscientific.com/p-img/STJ25661_3_IHC__78693.1602784740.jpg)
Immunohistochemistry of paraffin-embedded mouse embryos using [KO Validated] SOX2 Rabbit pAb (STJ25661) at dilution of 1:100 (40x lens).
Western blot analysis of extracts from normal (control) and SOX2 Rabbit pAb knockout (KO) 293T cells, using SOX2 Rabbit pAb antibody (STJ110124) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 30s.
Western blot analysis of extracts of various cell lines, using SOX2 antibody (STJ25661) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 90s.
Anti-SOX2 antibody
Anti-SOX2 antibody
Catalog Number:
A001035068STJ
Mfr. No.:
STJ25661
Price:
$297
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