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Overview
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This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT).
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Overview
Confocal immunofluorescence analysis of U-2 OS cells using SOX2 Polyclonal Antibody (STJ113816) at dilution of 1:200. Blue: DAPI for nuclear staining.
Immunofluorescence analysis of C6 cells using SOX2 Polyclonal Antibody (STJ113816) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
Immunofluorescence analysis of HeLa cells using SOX2 Polyclonal Antibody (STJ113816) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
Western blot analysis of extracts of various cell lines, using SOX2 antibody (STJ113816) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 90s.
Anti-SOX2 antibody
Anti-SOX2 antibody
Catalog Number:
A001020907STJ
Mfr. No.:
STJ113816
Price:
$297
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