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Overview
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This gene encodes a member of the VPS10-related sortilin family of proteins. The encoded preproprotein is proteolytically processed by furin to generate the mature receptor. This receptor plays a role in the trafficking of different proteins to either the cell surface, or subcellular compartments such as lysosomes and endosomes. Expression levels of this gene may influence the risk of myocardial infarction in human patients. Alternative splicing results in multiple transcript variants.
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- Properties
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Overview
Immunohistochemistry of paraffin-embedded human kidney using SORT1 antibody (STJ110235) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded mouse liver using SORT1 antibody (STJ110235) at dilution of 1:100 (40x lens).
Western blot analysis of extracts of various cell lines, using SORT1 antibody (STJ110235) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 90s.
Anti-SORT1 antibody
Anti-SORT1 antibody
Catalog Number:
A001017083STJ
Mfr. No.:
STJ110235
Price:
$297
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