Name: Anti-SOCS-1 antibody
Price: 224.00 USD

Overview
- SOCS-1 is a protein encoded by the SOCS1 gene which is approximately 23, 5 kDa. SOCS-1 is localised to the nucleus and cytoplasm. It is involved in activated TLR4 signalling, the prolactin signalling pathway, IL-2 pathway and class I MHC mediated antigen processing and presentation. This protein is a member of the suppressor of cytokine signalling family. It forms part of a negative feedback system that regulates cytokines that signal through the JAK/STAT3 pathway. SOCS-1 is expressed in all tissues with high expression in spleen, small intestine and peripheral blood leukocytes. Mutations in the SOCS1 gene may result in ileum cancer and infectious anterior uveitis. STJ95727 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of SOCS-1 protein.
  
  Please contact us at for specific academic pricing.
Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human; mouse; rat
  
  Immunogen
  
  Synthesized peptide derived from human SOCS-1.
  
  Purification
  
  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  
  Storage
  
  Store at -20°C and avoid repeat freeze-thaw cycles.
  
  Concentration
  
  1 mg/ml
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  Suppressor Of Cytokine Signaling 1; Socs-1; Jak-Binding Protein; Jab; Stat-Induced Stat Inhibitor 1; Ssi-1; Tec-Interacting Protein 3; Tip-3 (Gene ID:8651; UniProt:O15524)
  
  * For research use only