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Overview
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This gene is a member of the mitochondrial carrier family. The encoded protein contains four EF-hand Ca(2+) binding motifs in the N-terminal domain, and localizes to mitochondria. The protein catalyzes the exchange of aspartate for glutamate and a proton across the inner mitochondrial membrane, and is stimulated by calcium on the external side of the inner mitochondrial membrane. Mutations in this gene result in citrullinemia, type II. Multiple transcript variants encoding different isoforms have been found for this gene.
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- Properties
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Overview
Immunofluorescence analysis of U2OS cells using SLC25A13 antibody (STJ114431). Blue: DAPI for nuclear staining.
Immunohistochemistry of paraffin-embedded human lung cancer using SLC25A13 antibody (STJ114431) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human colon carcinoma using SLC25A13 antibody (STJ114431) at dilution of 1:100 (40x lens).
Western blot analysis of extracts of various cell lines, using SLC25A13 antibody (STJ114431) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 90s.
Anti-SLC25A13 antibody
Anti-SLC25A13 antibody
Catalog Number:
A001021394STJ
Mfr. No.:
STJ114431
Price:
$297
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