Anti-SIRT4 antibody

Catalog Number:

A001037673STJ

Mfr. No.:

STJ29722

Price:

$297

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Overview
- This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family.
  
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Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human; mouse; rat
  
  Immunogen
  
  Recombinant fusion protein containing a sequence corresponding to amino acids 29-260 of human SIRT4 (NP_036372. 1).
  
  Purification
  
  Affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  
  Storage
  
  Store at -20°C and avoid freeze-thaw cycles.
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  Nad-Dependent Protein Lipoamidase Sirtuin-4-Mitochondrial; Nad-Dependent Adp-Ribosyltransferase Sirtuin-4; Nad-Dependent Protein Deacetylase Sirtuin-4; Regulatory Protein Sir2 Homolog 4; Sir2-Like Protein 4 (Gene ID:23409; UniProt:Q9Y6E7)
  
  * For research use only