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Overview
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This gene encodes a ubiquitously expressed nuclear protein which belongs to a highly conserved subfamily of WD-repeat proteins. The encoded protein binds directly to retinoblastoma protein, which regulates cell proliferation. It interacts preferentially with the underphosphorylated retinoblastoma protein via the E1A-binding pocket B. Three alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.
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Overview
Immunofluorescence analysis of A-549 cells using RBBP5 antibody (STJ29045). Blue: DAPI for nuclear staining.
Immunohistochemistry of paraffin-embedded mouse liver using RBBP5 antibody (STJ29045) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded rat Intestine using RBBP5 antibody (STJ29045) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human colon carcinoma using RBBP5 antibody (STJ29045) at dilution of 1:100 (40x lens).
Western blot analysis of extracts of various cell lines, using RBBP5 antibody (STJ29045) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 10s.
Anti-RBBP5 antibody
Anti-RBBP5 antibody
Catalog Number:
A001037075STJ
Mfr. No.:
STJ29045
Price:
$297
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