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Overview
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This gene encodes a retinoic acid receptor that belongs to the nuclear hormone receptor family. Retinoic acid receptors (RARs) act as ligand-dependent transcriptional regulators. When bound to ligands, RARs activate transcription by binding as heterodimers to the retinoic acid response elements (RARE) found in the promoter regions of the target genes. In their unbound form, RARs repress transcription of their target genes. RARs are involved in various biological processes, including limb bud development, skeletal growth, and matrix homeostasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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- Properties
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Overview
Immunofluorescence analysis of A549 cells using RARG antibody (STJ29584). Blue: DAPI for nuclear staining.
Western blot analysis of extracts of various cell lines, using RARG antibody (STJ29584) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 30s.
Anti-RARG antibody
Anti-RARG antibody
Catalog Number:
A001037553STJ
Mfr. No.:
STJ29584
Price:
$297
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