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Overview
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The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. This PTP has been shown to dephosphorylate and activate Src family tyrosine kinases, and is implicated in the regulation of integrin signaling, cell adhesion and proliferation. Three alternatively spliced variants of this gene, which encode two distinct isoforms, have been reported.
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Overview
Immunohistochemistry of paraffin-embedded human stomach using PTPRA Antibody (STJ25230) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human colon using PTPRA Antibody (STJ25230) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human kidney using PTPRA Antibody (STJ25230) at dilution of 1:100 (40x lens).
Western blot analysis of extracts of various cell lines, using PTPRA antibody (STJ25230) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit.Exposure time: 90s.
Anti-PTPRA antibody
Anti-PTPRA antibody
Catalog Number:
A001034832STJ
Mfr. No.:
STJ25230
Price:
$297
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