Anti-PRDM2 antibody

Catalog Number:

A001019147STJ

Mfr. No.:

STJ111300

Price:

$297

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Overview
- This tumor suppressor gene is a member of a nuclear histone/protein methyltransferase superfamily. It encodes a zinc finger protein that can bind to retinoblastoma protein, estrogen receptor, and the TPA-responsive element (MTE) of the heme-oxygenase-1 gene. Although the functions of this protein have not been fully characterized, it may (1) play a role in transcriptional regulation during neuronal differentiation and pathogenesis of retinoblastoma, (2) act as a transcriptional activator of the heme-oxygenase-1 gene, and (3) be a specific effector of estrogen action. Multiple transcript variants encoding different isoforms have been found for this gene.
  
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Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  rat
  
  Immunogen
  
  Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human PRDM2 (NP_036363. 2).
  
  Purification
  
  Affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  
  Storage
  
  Store at -20°C and avoid freeze-thaw cycles.
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  Pr Domain Zinc Finger Protein 2; Gata-3-Binding Protein G3b; Lysine N-Methyltransferase 8; Mtb-Zf; Mte-Binding Protein; Pr Domain-Containing Protein 2; Retinoblastoma Protein-Interacting Zinc Finger Protein; Zinc Finger Protein Riz (Gene ID:7799; UniProt:Q13029)
  
  * For research use only