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Overview
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This gene encodes the penultimate enzyme of heme biosynthesis, which catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX. Mutations in this gene cause variegate porphyria, an autosomal dominant disorder of heme metabolism resulting from a deficiency in protoporphyrinogen oxidase, an enzyme located on the inner mitochondrial membrane. Alternatively spliced transcript variants encoding the same protein have been identified.
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Overview
Immunohistochemistry of paraffin-embedded human colon carcinoma using PPOX antibody (STJ28480) at dilution of 1:100 (40x lens).
Immunofluorescence analysis of MCF7 cells using PPOX antibody (STJ28480). Blue: DAPI for nuclear staining.
Western blot analysis of extracts of various cell lines, using PPOX Antibody (STJ28480) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit.Exposure time: 90s.
Anti-PPOX antibody
Anti-PPOX antibody
Catalog Number:
A001036576STJ
Mfr. No.:
STJ28480
Price:
$297
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