Anti-POU2F3 antibody

Catalog Number:

A001019858STJ

Mfr. No.:

STJ112094

Price:

$297

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Overview
- This gene encodes a member of the POU domain family of transcription factors. POU domain transcription factors bind to a specific octamer DNA motif and regulate cell type-specific differentiation pathways. The encoded protein is primarily expressed in the epidermis, and plays a critical role in keratinocyte proliferation and differentiation. The encoded protein is also a candidate tumor suppressor protein, and aberrant promoter methylation of this gene may play a role in cervical cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
  
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Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  mouse
  
  Immunogen
  
  Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human POU2F3 (NP_055167. 2).
  
  Purification
  
  Affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  
  Storage
  
  Store at -20°C and avoid freeze-thaw cycles.
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  Pou Domain-Class 2-Transcription Factor 3; Octamer-Binding Protein 11; Oct-11; Octamer-Binding Transcription Factor 11; Otf-11; Transcription Factor Pla-1; Transcription Factor Skn-1 (Gene ID:25833; UniProt:Q9UKI9)
  
  * For research use only