Anti-POLR2B antibody

Catalog Number:

A001036100STJ

Mfr. No.:

STJ27724

Price:

$297

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Overview
- This gene encodes the second largest subunit of RNA polymerase II (Pol II), a DNA-dependent RNA polymerase that catalyzes the transcription of DNA into precursors of mRNA, snRNA and microRNA. This subunit and the largest subunit form opposite sides of the center cleft of Pol II. Deletion of the flap loop region of this subunit results in a decrease in the rate of transcriptional elongation. Alternative splicing results in multiple transcript variants.
  
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Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human; mouse; rat
  
  Immunogen
  
  Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human POLR2B (NP_000929. 1).
  
  Purification
  
  Affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  
  Storage
  
  Store at -20°C and avoid freeze-thaw cycles.
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  Dna-Directed Rna Polymerase II Subunit Rpb2; Dna-Directed Rna Polymerase II 140 Kda Polypeptide; Dna-Directed Rna Polymerase II Subunit B; Rna Polymerase II Subunit 2; Rna Polymerase II Subunit B2 (Gene ID:5431; UniProt:P30876)
  
  * For research use only