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Overview
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The protein encoded by this gene catalyzes the isomerization of mannose 6-phosphate to mannose 1-phosphate, which is a precursor to GDP-mannose necessary for the synthesis of dolichol-P-oligosaccharides. Mutations in this gene have been shown to cause defects in glycoprotein biosynthesis, which manifests as carbohydrate-deficient glycoprotein syndrome type I.
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- Properties
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Overview
Immunohistochemistry of paraffin-embedded human prostate using PMM2 antibody (STJ25035) at dilution of 1:100 (40x lens).
Immunofluorescence analysis of L929 cells using PMM2 antibody (STJ25035) at dilution of 1:100. Blue: DAPI for nuclear staining.
Western blot analysis of extracts of various cell lines, using PMM2 antibody (STJ25035) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 60s.
Anti-PMM2 antibody
Anti-PMM2 antibody
Catalog Number:
A001034706STJ
Mfr. No.:
STJ25035
Price:
$297
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