Anti-PLCB2 antibody

Catalog Number:

A001017257STJ

Mfr. No.:

STJ110440

Price:

$297

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Overview
- The protein encoded by this gene is a phosphodiesterase that catalyzes the hydrolysis of phosphatidylinositol 4, 5-bisphosphate to the second messengers inositol 1, 4, 5-trisphosphate (IP3) and diacylglycerol. The encoded protein is activated by G proteins and has been shown to be involved in the type 2 taste receptor signal transduction pathway. In addition, nuclear factor kappa B can regulate the transcription of this gene, whose protein product is also an important regulator of platelet responses.
  
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Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human; mouse; rat
  
  Immunogen
  
  Recombinant fusion protein containing a sequence corresponding to amino acids 1-199 of human PLCB2 (NP_001271228. 1).
  
  Purification
  
  Affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  
  Storage
  
  Store at -20°C and avoid freeze-thaw cycles.
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  1-Phosphatidylinositol 4-5-Bisphosphate Phosphodiesterase Beta-2; Phosphoinositide Phospholipase C-Beta-2; Phospholipase C-Beta-2; Plc-Beta-2 (Gene ID:5330; UniProt:Q00722)
  
  * For research use only