Name: Anti-Phospho-MAP2K4-(S257/T261) antibody
Price: 295.00 USD

Overview
- This gene encodes a member of the mitogen-activated protein kinase (MAPK) family. Members of this family act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. They form a three-tiered signaling module composed of MAPKKKs, MAPKKs, and MAPKs. This protein is phosphorylated at serine and threonine residues by MAPKKKs and subsequently phosphorylates downstream MAPK targets at threonine and tyrosine residues. A similar protein in mouse has been reported to play a role in liver organogenesis. A pseudogene of this gene is located on the long arm of chromosome X. Alternative splicing results in multiple transcript variants.
  
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Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human
  
  Immunogen
  
  A phospho specific peptide corresponding to residues surrounding S257/T261 of human MAP2K4
  
  Purification
  
  Affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  
  Storage
  
  Store at -20°C and avoid freeze-thaw cycles.
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  Dual Specificity Mitogen-Activated Protein Kinase Kinase 4; Map Kinase Kinase 4; Mapkk 4; Jnk-Activating Kinase 1; Mapk/Erk Kinase 4; Mek 4; Sapk/Erk Kinase 1; Sek1; Stress-Activated Protein Kinase Kinase 1; Sapk Kinase 1; Sapkk-1; Sapkk1; C-Jun N-Terminal Kinase Kinase 1; Jnkk (Gene ID:6416; UniProt:P45985)
  
  * For research use only